The Fehl Lab is passionate about developing chemical tools to unravel the complex mechanisms cells use to regulate their gene expression. We apply these tools to the diseased metabolic aspects of cancer, diabetes, and neurodegeneration, in particular by manipulating how cells use sugar levels as key signaling regulators.
Our key techniques include organic synthesis, biocatalysis, cell culture, proteomics, and bioinformatics to identify signaling pathways to reprogram pathological epigenetic pathways in disease.
Nov 14, 2019 Congratulations to Jessica for achieving a Eugine Perrin Science and Peace Fellowship from Wayne State University! We will march one step closer to world harmony using her anti-diabetes peptide probes.
Mole Day, 2019 (October 23rd) We pulled it off! The Wayne State American Chemical Society Student Affiliates (Chem Club), co-advised by Charlie Fehl and Sue White, constructed the World’s Largest Periodic Table of the Elements for STEM outreach:
Thanks to WSU, University of Detroit-Mercy, the University of Michigan (Flint and Dearborn campuses), Lawrence Technological University, and the Detroit Local Section of the American Chemical Society for support and volunteers!
June 27, 2019 Congratulations to Zack who was awarded an Initiative for Maximizing Student Diversity Fellowship from the Wayne State Medical School!
June 23, 2019 More Fehl Lab exposure at Carbohydrates Gordon Research Conference!
June 2, 2019 Fehl Lab exposure at the High Throughput Chemistry and Chemical Biology Gordon Research Conference
March 16, 2019 Neinas Academy joins the Fehl group for fun with science. Well-handled by the group…though Jessica looks concerned about proper technique!
January 21, 2019 Dr. Jaggaiah Naidu joins us as a postdoctoral scholar specializing in carbohydrate synthetic chemical biology. Welcome!
Oct 13, 2018 Charlie is selected to give the keynote lecture at the ACS Detroit Chapter “Chemistry in the Motor City” Symposium. Great talks from UT, OSU, Umich, and WSU!
Sept 15th, 2018 Minor equipment failure (the light switches) gives a cool photo op: –> Doug and Ali getting our E. coli strains up and running
September, 2018 The lab begins! We welcome Ali, Doug, and Anthony–Undergrad Research Assistants–and Yimin, lab manager, to drive our tissue culture, molecular biology, and bioinformatics!
August 15, 2018 Goodbye old equipment – more space for rotavaps!
August 8, 2018 The Fehl Lab officially opens! I look forward to meeting the new class of WSU Chemists!
April 7, 2018 Charlie is honored to join Wayne State Chemistry to study the epigenetic signaling pathways of sugar-protein conjugates. The lab-building begins…